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hPD-L1/hLAG3

Background : C57BL/6Smoc

Catalog : NM-HU-00137

Strain Name : C57BL/6Smoc-Cd274^em1(hPD-L1)Lag3^{tm1(hLAG3)Smoc}

Gene Summary

Gene Name

Synonyms :
B7h1， Pdl1， Pdcd1l1，Pdcd1lg1， A530045L16Rik, Ly66， CD223， LAG-3
NCBI ID :
60533 16768
MGI ID :
1926446 106588
Ensembl ID :
ENSMUSG00000016496 ENSMUSG00000030124
Strain State :
胚胎冻存

Model Description

hPD-L1（NM-HU-00062）was crossed with hLAG3（NM-HU-00049）to generate hPD-L1/hLAG3.

Validation Data

pd-l1&lag3.png

Fig1 Splenocytes from homozygous hPDL1/hLAG3 mice were analyzed by flow cytometry after activation. mPDL1+ and mLAG3+ were detectable in wild type (WT) C57BL/6, while hPDL1+ and hLAG3+ cells were detectable in the homozygous hPDL1/hLAG3 mice.

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