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Home / Toolbox of Mice / Find Cre / Drd1-2A-CreERT2

Drd1-2A-CreERT2

Background : C57BL/6Smoc

Catalog : NM-KI-18016

Strain Name :

C57BL/6Smoc-Drd1em1(2A-CreERT2-WPRE-pA)Smoc

Gene Summary

Gene Name

Model Description

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Drd1 gene via homologous recombination to establish a tamoxifen inducible Drd1-CreERT2 tool stain. This strain can be used to knockout target gene in Drd1+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Validation Data

验证数据-Drd1a-CreERT2-图片1.png

Figure 1：CreERT2-mediated recombination in brain of Drd1a CreERT2; R26 tdTomato mice. Detection of tdTomato (red) in brain of Drd1a CreERT2; R26 tdTomato mice.

验证数据-Drd1a-CreERT2-图片2.png

Figure 2：CreERT2-mediated recombination in CPU(corpus striatum) of Drd1a CreERT2; R26 tdTomato mice. Detection of tdTomato (red) in CPU of Drd1a CreERT2; R26 tdTomato mice.

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