hTLR9

Background : C57BL/6Smoc

Catalog : NM-HU-18016

Strain Name :

C57BL/6Smoc-Tlr9tm1(hTLR9)Smoc

Gene Summary

Gene Name

Model Description

This TLR9 humanized mouse model was established by replacing the mouse Tlr9 gene exon2 with the human TLR9 corresponding sequence by homologous recombination.

Validation Data

image.png

Fig.1 Detection of hTLR9 and mTlr9 expression in Peripheral blood in WT C57BL/6 and HO hTLR9 KI mice. 

image.pngFig.2 Detection of hTLR9 and mTlr9 expression in Spleen in WT C57BL/6 and HO hTLR9 KI mice.

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