Cdh1-2A-DreERT2

Background : C57BL/6Smoc

Catalog : NM-KI-190031

Strain Name : C57BL/6Smoc-Cdh1em3(2A-DreERT2)Smoc

Gene Summary

Gene Name
  • Synonyms :

    Ecad, E-cad, E-cadherin, L-CAM, UM, uvomorulin

  • NCBI ID :

    12550

  • MGI ID :

    88354

  • Ensembl ID :

    ENSMUSG00000000303

  • Strain State :

    精子冻存

Model Description

A 2A-DreERT2 expression cassette was knocked into the Cdh1 gene stop codon site via CRISPR/Cas mediated recombination.

Validation Data

image.png

Fig. 1 DreERT2-mediated recombination in the liver of Cdh1DreERT2/+;R26tdtomato/+ mouse. Tdtomato (red) expression can be detected in the liver after tamoxifen treatment. Cdh1 gene encodes E-cadherin(E-CAD), a calcium-dependent adhesion  molecule that expressed primarily in epithelial cells. (Documented in the following reference.)


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