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B2m-KO(NMG)

Background : NOD.Cg

Catalog : NM-NSG-002

Strain Name :

NOD.Cg-Prkdc^scidIl2rg^em1SmocB2m^em1Smoc

Gene Summary

Gene Name

Synonyms :
beta2-m, beta 2 microglobulin, Ly-m11
NCBI ID :
12010
MGI ID :
88127
Ensembl ID :
ENSMUSG00000060802
Pubmed :
Array
Strain State :
活体

Model Description

This B2m knockout mouse model was obtained by knocking out the exon 2-3 region of mouse B2m gene on the background of NMG mouse.

Validation Data

Fig1. Detection of B2m expression in cerebellum by RT-PCR.

Wild type: only one band at 139 bp with primers F1/R1(mB2m);

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

Fig2. Expression characterization of mouse MHC I and MHC II in bone marrow, blood, spleen in B2m-KO(M-NSG) mice.

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Background

hIL3(NMG)

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huHSC-(NMG)

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hANGPTL3(3)

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hCTLA-4/hCD28(BALB/c)

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hIL6

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hETAR

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hITGB8

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hFCGR3A

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