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Home / Humanized Models / Immune Checkpoints / hSIGLEC15(BALB/c)

hSIGLEC15(BALB/c)

Background : BALB/cAnSmoc

Catalog : NM-HU-200001

Strain Name :

BALB/cAnSmoc-Siglec15em2(hSIGLEC15) Smoc

Gene Summary

Gene Name

Model Description

The endogenous mouse Siglec15 gene was replaced by human SIGLEC15 gene .

Validation Data

image.png

Fig1. Analysis of hSIGLEC15 expression on macrophages in the SIGLEC15 humanized mice. The homozygous humanized mice express hSIGLEC15 on peritioneal macrophages but not marrow macrophages.

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