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R26-CreERT2

Background : C57BL/6Smoc

Catalog : NM-KI-200041

Strain Name :

C57BL/6Smoc-Gt(ROSA)26Sor^{em1(SA-FRT-2xpolyA-CAG-FRT-CreERT2-Rox-WPRE-Rox-polyA)Smoc}

Gene Summary

Gene Name

Synonyms :
R26, ROSA26, AV258896, Gtrgeo26, Gtrosa26, Thumpd3as1
NCBI ID :
14910
MGI ID :
104735
Ensembl ID :
ENSMUSG00000086429
Strain State :
Repository Live

Model Description

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-CreERT2-Rox-WPRE-Rox-polyA cassette in the Rosa26 locus generated by homologous recombination. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in multiple tissues after tamoxifen treatment.

Validation Data

Fig1. Detection of tdTomato(red) in various tissues of R26CreERT2/+; Rosa26tdTomato/+ mice by fluorescence assay. Expression tissues include: brain, liver, stomach, thymus, pancreas, colon, heart, kidney and spleen. (For more detailed information please contact our technical advisor.)

Fig2. CreERT2-mediated recombination in peripheral blood of R26CreERT2/+; Rosa26tdTomato/+ mice.

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