Glp1r-IRES-Cre

Background : C57BL/6Smoc

Catalog : NM-KI-200134

Strain Name : C57BL/6Smoc-Glp1rem1(IRES-iCre)Smoc

Gene Summary

Gene Name

Model Description

A IRES-iCre expression cassette was knocked into the Glp1r gene stop codon site.

Validation Data

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Fig. 1 Cre-mediated recombination in the small intestine of Glp1rCre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the muscular layer of the wall of the small intestine derived from Glp1rCre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Cre-mediated recombination in the pancreas of Glp1rCre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the acinar and islet cells of Glp1rCre/+; Rosa26tdTomato/+ mouse.

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Fig. 3 Cre-mediated recombination in the brain of Glp1rCre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in individual cells of olfactory bulb, cortex, interbrain, thalamus and hypothalamus derived from Glp1rCre/+; Rosa26tdTomato/+ mouse.

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Fig. 4 Detection of tdTomato(red) in various tissues of Glp1rCre/+; Rosa26tdTomato/+ mice. Cre mediated recombination can be detected in some cells of pancreas. TdTomato can also be detected in individual cells of the brain, intestine, colon, heart, lung, liver, stomach, submandibular gland, testis, epididymis, skin, skeletal muscle and spleen. Tdtomato expression can not be observed in the brown fat, thymus or retina. (For more detailed information please contact our technical advisor.)


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