MC38-hCD47

Background : MC38

Catalog : NM-S13-TM05

Strain Name :

MC38-Cd47em1(hCD47)/Smoc

Gene Summary

Gene Name

Model Description

The endogenous mouse Cd47 gene was replaced by human CD47 gene.

Validation Data

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Figure 1. hCD47 expression in wild-type MC38 and MC38-hCD47 cell lines.

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Figure 2. Tumor growth curve of MC38-hCD47 syngeneic model (n=5).

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Figure 3. Body weight change of MC38-hCD47 syngeneic model (n=5).

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Figure 4. The expression of hCD47 in humanized modified tumors by FACS.

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Figure 5. Antitumor activity of antibody (n=8).

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