hDLL3

Background : C57BL/6Smoc

Catalog : NM-HU-200231

Strain Name : C57BL/6Smoc-Dll3em1(hDLL3)Smoc

Gene Summary

Gene Name

Model Description

The endogenous mice Dll3 gene was replaced by human DLL3 gene.

Validation Data

image.png

Fig.1 Detection of DLL3 expression in brain by RT-PCR. 

Wild type: only one band at 293 bp with primers F1/R1 (mDll3);

Homozygous: only one band at 282 bp with primers F2/R2 (hDLL3).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human DLL3 expression in hDLL3 knockin mice by WB. 

Abbr. HO, homozygous; WT, wild type.

Note: The anti-human DLL3 antibody cross-reacted with mouse DLL3 and humanized DLL3.


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