hNCR3

Background : C57BL/6Smoc

Catalog : NM-HU-215066

Strain Name :

C57BL/6Smoc-Ncr1em1(hNCR3)Smoc

Gene Summary

Gene Name

Model Description

The endogenous mouse Ncr1 gene was replaced by human NCR3 gene.

Validation Data

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Fig1. Detection of NCR3 expression in spleen by RT-PCR. Wild type: only one band at 230 bp with primers F1/R1(mNcr1);Heterozygous: one band at 230 bp with primers F1/R1(mNcr1) and one band at 291 bp with primers F2/R2(hNCR3); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig2. Analysis of hNCR3(CD337) expression on NK cells in PB by FACS.

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Fig3. Analysis of hNCR3(CD337) expression on NK cells in spleen by FACS.

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