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hIL5/hIL5R(3)

Background : C57BL/6Smoc

Catalog : NM-HU-220011

Strain Name : C57BL/6Smoc-Il5^tm3(hIL5)Il5ra^{em3(hIL5RA)Smoc}

Gene Summary

Gene Name

Synonyms :
Il-5, Il5r, CD125, CDw125
NCBI ID :
16191 16192
MGI ID :
96557 96558
Ensembl ID :
ENSMUSG00000036117 ENSMUSG00000005364
Strain State :
活体

Model Description

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(2)(Stock No.NM-HU-220010) function similarly to hIL5/hIL5R(3) mice, for more detailed information please contact our technical advisor.

Validation Data

Fig1. Expression of hIL5R on Bone marrow-derived eosinophils in hIL5/hIL5R(3) dKI mice.

Note: Eosinophils were derived from bone marrow cells through culture with rmSCF, rmFLT-3L, and rmlL-5.

Related Strains

Product

Product Catalog

Background

hIL3(NMG)

NM-NSG-007

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huHSC-(NMG)

NM-NSG-017

huHSC

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R26-CAG-LSL-hFCGR2A-IRES-EGFP

NM-KI-200229

C57BL/6Smoc

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R26-CAG-LSL-hFCGR3A-IRES-tdTomato

NM-KI-200255

C57BL/6Smoc

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R26-CAG-LSL-hSOS-F-tdTomato

NM-KI-200020

C57BL/6Smoc

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hTNFRSF10C

NM-HU-230344

C57BL/6Smoc

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R26-CAG-LSL-hMLL-AF9-IRES-Luc-2A-tdTomato

NM-KI-190114

C57BL/6Smoc

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hTIM4

NM-HU-225042

C57BL/6Smoc

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hANGPTL3(3)

NM-HU-210037

C57BL/6Smoc

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hFCGR1A

NM-HU-2000072

C57BL/6Smoc

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