Prg4-CreERT2-2A-EGFP

Background : C57BL/6Smoc

Catalog : NM-KI-225074

Strain Name :

C57BL/6Smoc-Prg4em(Kozak-CreERT2-2A-EGFP-WPRE-pA)1Smoc

Gene Summary

Gene Name

Model Description

Kozak-CreERT2-2A-EGFP-WPRE-pA expression cassette was knocked into the Prg4 gene .

Validation Data

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Fig 1. Cre-mediated recombination in bone of Prg4CreERT2-EGFP/+; Rosa26tdTomato/+ mice.

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Fig 2. Detection of tdTomato (red) and GFP (green) in various tissues of Prg4CreERT2-EGFP/+; Rosa26tdTomato/+ mice. Expression tissues include: liver, bone, spleen, muscle, hair follicle. A few cells expressed in heart, salivary gland, adrenal gland, small intestine, testis. Tissues that unexpressed include brain, spinal cord, retina, lung, stomach, brown fat, kidney, colon, pancreas, thymus, pituitary. (37-day old, male) 

TdTomato labeling was observed in tissue sections of Prg4CreERT2-EGFP/+;Rosa26tdTomato/+ untreated treated groups, indicating spontaneous Cre activity in the absence of tamoxifen.

(For more detailed information please contact our technical advisor.) 

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