hIL11/hIL11RA

Nomenclature

C57BL/6Smoc-Il11em1(hIL11)Il11ra1tm1(hIL11RA)/Smoc

Cat. NO.

NM-HU-210372

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Tnfrsf4

Synonyms

Ox40; ACT35; CD134; Ly-70; Txgp1; TXGP1L

NCBI ID

22163

MGI ID

104512

Ensembl ID

ENSMUSG00000029075

Pubmed

Tnfrsf4

Human Ortholog

TNFRSF4

Gene Symbol
Il11ra1

Synonyms

NR1; GP130; Il11ra; Il-11ra; Il11ra2; AI314697

NCBI ID

16157

MGI ID

107426

Ensembl ID

ENSMUSG00000073889

Pubmed

Il11ra1

Human Ortholog

IL11RA1

Model Description

hIL11(NM-HU-204981) was crossed with hIL11RA (NM-HU-204982) to generate hIL11/hIL11RA mice.
Research Application：inmmue therapy;drug screening

Validation Data

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Fig1. Detection of hIL11 expression in lung homogenate by ELISA. Abbr. HO, homozygous; WT, wild type. Note. hIL11/hIL11RA and C57BL/6 mice were injected with LPS.

image.png

Fig2. Detection of hIL11RA expression in Kidney in C57BL/6 and HO/HO hIL11/hIL11RA knockin mice by IHC. Abbr. HO/HO, homozygous; WT, wild type. Note. The anti-human IL11RA Antibody cross-reacted with mouse IL11RA and humanized IL11RA.

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