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U-GEMMs

About 42,513 results
Mice

hSPP1

Strain Name:C57BL/6Smoc-Spp1tm1(hSPP1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-225037

The endogenous mouse Spp1 gene was replaced by human SPP1 gene.

Mice

hLAG3

Strain Name:B6.129S-Lag3tm1(hLAG3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00049

The endogenous mouse Lag3 gene exon1-7 was replaced by human LAG3 gene extracellular region by homologous recombination.

Mice

hCXCR3

Strain Name:C57BL/6Smoc-Cxcr3em1(hCXCR3)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200219

The endogenous mouse Cxcr3 gene was completely or partially replaced by human CXCR3 gene via ESC targeting.

Mice

Axin2-CreERT2

Strain Name:C57BL/6Smoc-Axin2em1(CreERT2-pA)Smoc
Strain State:Developing | Cat. NO.:NM-KI-200109

A CreERT2-pA expression cassette was knocked into the Axin2 gene start codon site. As Axin2 is an intracellular protein, it is essential for identifying a surface marker for stem cell purification. When these Axin2-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Axin2 expressing cells.

Mice

hFCGR2A

Strain Name:C57BL/6Smoc-Fcgr2bem3(hFCGR2A)/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-2000071

The endogenous mouse Fcgr2b gene was replaced by human FCGR2A gene.

Mice

Il1b-Luc-2A-EGFP

Strain Name:C57BL/6Smoc-Il1bem1(Luc-eGFP)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-00010

A Luciferase-2A-EGFP-pA cassette was inserted at ATG site of mouse Il1b gene. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il1b.

Mice

hSIRPA/hCD47(BALB/c)

Strain Name:BALB/cAnSmoc-Sirpatm4(hSIRPA)/SmocCd47em1(hCD47)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210020

hCD47 (NM-HU-00050) and hSRPA(2)(NM-HU-18015) were bred with BALB/c mice respectively to generate hSIRPA/hCD47(BALB/c) mice.

Mice

hPTPN1

Strain Name:C57BL/6Smoc-Ptpn1tm1(hPTPN1)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-225059

The endogenous mouse Ptpn1 gene was replaced by human PTPN1 gene.

Mice

Rag2/IL2rg-KO/hVEGFR2

Strain Name:C57BL/6Smoc-Il2rgem1Kdrtm2(hKDR)Rag2em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220087

IL2rg-KO (NM-KO-210098) mice were crossed with Rag2-KO/hKDR (NM-HU-200280) mice to generate Rag2/IL2rg-KO/hKDR mouse models.

Mice

hIGHG1

Strain Name:C57BL/6Smoc-Ighg1tm1(hIGHG1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225091

The endogenous mouse Ighg1 gene was replaced by human IGHG1 gene.

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