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Home / Toolbox of Mice / Find Cre / Avp-IRES-Cre

Avp-IRES-Cre

Background : C57BL/6Smoc

Catalog : NM-KI-200142

Strain Name : C57BL/6Smoc-Avpem1(IRES2-Cre-WPRE-polyA)Smoc

Gene Summary

Gene Name

Model Description

A IRES2-Cre-WPRE-polyA expression cassette was knocked into the Avp gene stop codon site. Avp encodes arginine vasopressin. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying hypertension.

Validation Data

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Fig. 1 Cre-mediated recombination in the brain of AvpCre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the suprachiasmatic nucleus (SCN) of AvpCre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Detection of tdTomato(red) in various tissues of AvpCre/+; Rosa26tdTomato/+ mice. Cre mediated recombination can be detected in some cells of the brian, kidney, intestine, colon, eyes, brown fat, testis, epididymis, salivary gland, stomach, thymus, liver, pancreas, muscle, spleen and heart. (For more detailed information please contact our technical advisor.)


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