Strain Model Specification

Cckbr-KO

Strain Name C57BL/6Smoc-Cckbrem1Smoc
Catalog Number NM-KO-190609
Genetic Background C57BL/6Smoc
Gene Symbol Cckbr
Synonyms CCK2R, CCK-BR, CCK2-R, CCKR-2
NCBI ID 12426 ↗
MGI ID 99479 ↗
Ensembl ID ENSMUSG00000030898 ↗
Strain State Sperm cryopreservation
Research Application This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors.