Cd19-IRES-DTRGFP

Validation data of EGFP expression

Fig1.  Validation EGFP expression in PBMC by FACS. (Cooperation with CrownBio)

Validation data of DTR function

Heterozygous Cd19-IRES-DTRGFP mice and C57BL/6 mice were inoculated with MC38 colon cancer cells. After the tumors grew to 100 mm3, the Cd19-IRES-DTRGFP mice were injected with Diphtheria toxin. 

Fig2. The growth of MC38 tumors in Heterozygous Cd19-IRES-DTRGFP mice and C57BL/6 mice. (Cooperation with CrownBio)

Fig3. The percent of CD19+ cell in peripheral blood of MC38 tumor-bearing Cd19-IRES-DTRGFP mice and C57BL/6 mice is detected by FACS. (Cooperation with CrownBio)

Fig4. The percent of CD19+ cell in peripheral blood of MC38 tumor-bearing Cd19-IRES-DTRGFP mice and C57BL/6 mice is detected by FACS. (Cooperation with CrownBio)