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Home / Cd274-KO(2)

Cd274-KO(2)

Background : C57BL/6Smoc

Catalog : NM-KO-18044

Strain Name :

C57BL/6Smoc-Cd274em2Smoc

Gene Summary

Gene Name
  • Synonyms :

    B7h1， Pdl1， Pdcd1l1，Pdcd1lg1， A530045L16Rik

  • NCBI ID :

    60533

  • MGI ID :

    1926446

  • Ensembl ID :

    ENSMUSG00000016496

  • Strain State :

    Repository Live

Model Description

Cd274 gene is also called B7-H1, Pdcd1lg1 or PD-L1. The PD-L1-KO(2) mouse model was obtained by deleting the Exon 3-5 region of mouse Cd274 gene. While PD-L1-KO(Stock No.NM-KO-00104) mice have been pulled from shelves for some reasons.

Validation Data

image.png

Fig1. Expression of PD-L1 in peritoneal macrophages, spleen cells and bone marrow cells from PD-L1 knockout mice is detected by FACS.  The results showed that the expression of PD-L1 can not be detected in peritoneal macrophages, spleen cells and bone marrow cells of homozygous mice.

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