Strain Model Specification

Cd8a-IRES-Luc-2A-EGFP

Strain Name C57BL/6Smoc-Cd8aem1(V5-IRES-luci-2A-EGFP)Smoc
Catalog Number NM-KI-18030
Genetic Background C57BL/6Smoc
Gene Symbol Cd8a
Synonyms Ly-2, Ly-35, Ly-B, Lyt-2
NCBI ID 12525 ↗
MGI ID 88346 ↗
Ensembl ID ENSMUSG00000053977 ↗
Strain State Embryo cryopreservation
Research Application gene tracing

Validation Data

Cd8a-V5-IRES-Akaluc-2A-EGFP mouse model_05.png

Figure 1  In the absence of any stimulation, the in vivo imaging system detected that Cd8aV5-IRES-luci-2A-EGFP/+ mice showed significant fluorescence.

Cd8a-V5-IRES-Akaluc-2A-EGFP mouse model_06.png

Figure 2  In vivo imaging validation of MC38 tumors in Cd8aV5-IRES-luci-2A-EGFP/+ reporter mice treated or not with a PD-1 mAb. After 1 day of stimulation with PD1 antibody, the fluorescence was significantly enhanced.

Cd8aV5-IRES-luci-2A-EGFP-3.png

Figure 3  EGFP expression analysis in  PBMC of Cd8aV5-IRES-luci-2A-EGFP/+ mice by flow cytometry.