Dbh-2A-Cre

Background : C57BL/6Smoc

Catalog : NM-KI-200210

Strain Name : C57BL/6Smoc-Dbhem1(2A-iCre)Smoc

Gene Summary

Gene Name

Model Description

A 2A-iCre expression cassette was knocked into the Dbh gene stop codon site via CRISPR/Cas9 mediated recombination.

Validation Data

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Fig. 1 Cre-mediated recombination in the brain of DbhCre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the brainstem of DbhCre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Detection of tdTomato(red) in various tissues of DbhCre/+; Rosa26tdTomato/+ mice. Tdtomato was expressed in the brain, pituitary gland, heart, muscle and lung. TdTomato can also be detected in individual cells of the liver, kidney, colon, intestine, stomach, pancreas, spleen, ovary and uterus. (For more detailed information please contact our technical advisor.)


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