Gad2-IRES-Cre

Background : C57BL/6Smoc

Catalog : NM-KI-200078

Strain Name : C57BL/6Smoc-Gad2em1(IRES-iCre-pA)Smoc

Gene Summary

Gene Name

Model Description

A IRES-iCre-pA expression cassette was knocked into the Gad2 gene stop codon site.

Validation Data

Gad2-iCre-1.png

Fig. 1 Detection of tdTomato (red) in the retina of Gad2icre/+; Rosa26tdTomato/+ mice. Cre-mediated recombination in the retinal ganglion cell layer (yellow arrow) and inner nuclear layer (red arrow) of Gad2iCre/+; Rosa26tdTomato/+ mouse. 

Gad2-iCre-2.png

Fig. 2 Detection of tdTomato (red) in some cells of the cortex and hippocampus drived from Gad2icre/+; Rosa26tdTomato/+ mice.

Gad2-iCre-3.png

Fig. 3 Detection of tdTomato (red) in various tissues of Gad2icre/+; Rosa26tdTomato/+ mice. Cre-mediated recombination in some cells of the brain, pituitary gland, retina, lung, heart, liver, submandibular gland, brown fat, kidney, pancreas, intestine, colon,  epididymis, muscle, skin and thymus can be observed. Tdtomato can not be detected in the spleen and testis. (For more detailed information please contact our technical advisor.)

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