Gla-KO

Background : C57BL/6Smoc

Catalog : NM-KO-200601

Strain Name :

C57BL/6Smoc-Gla^em1Smoc

Gene Summary

Gene Name

Exon 2-3 of Gla gene was deleted to generate Gla knockout mice.

Fig1. Detection of Gla expression in brain by RT-PCR (A) and qPCR (B).

Wild type: only one band at 268 bp with primers F1/R1(mGla).

Abbr. M, DNA marker; WT, wild type.

Fig2. Detection of serum GLA activity (A) and serum lyso-Gb3 levels (B) in 14 weeks old male Gla-KO mice. (Data from the collaborator)

Fig3. Hot plate test of 14 weeks old male Gla-KO mice. (Data from the collaborator)