Alb1, Alb-1, BCL002, FcRn
活体
Fig.1 Detection of hALB (A) and mALB (B) expression in serum by ELISA (n=3).
Abbr. HO, homozygous; WT, wild type.
Fig.2 Expression characterization of hFCRN in hALB/hFCRN dKI mice by Western blot. (Arrow indicates expected molecular weight and asterisk indicates a nonspecific band)
Fig.3 In vivo PK profiles of TAA scfv-anti HSA VHH in hALB/hFCRN mice (female, 10-12weeks, n=3 mice/timepoint).
(In cooperation with the third party).
Fig.4 Blood concentration curves of test articles in C57BL/6 and hFcRn/hALB dKI mice. (In cooperation with the third party)
Table 1 Noncompartmental Analysis (NAC) results of test articles in hFcRn/hALB dKI mice. (In cooperation with the third party)
Fig.5 Fitting curves of blood concentration in C57BL/6 and hFcRn/hALB dKI mice. (In cooperation with the third party)
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