hANGPTL3(3)

Background : C57BL/6Smoc

Catalog : NM-HU-210037

Strain Name :

C57BL/6Smoc-Angptl3em2(hANGPTL3)Smoc

Gene Summary

Gene Name

Model Description

The endogenous mice Angptl3 gene was replaced by human ANGPTL3 gene. While hANGPTL3(Stock No.NM-HU-200113) have been pulled from shelves for some reasons and hANGPTL3(4)(Stock No.NM-HU-210036) mice function similarly to hANGPTL3(3) mice, for more detailed information please contact our technical advisor.

Validation Data

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Fig1. Detection of ANGPTL3 expression in liver by RT-PCR. Wild type: only one band at 208 bp with primers F1/R1 (mAngptl3); Heterozygous: one band at 208bp with primers F1/R1 (mAngptl3) and one band at 325 bp with primers F2/R2 (hANGPTL3); Abbr. M, DNA marker; HE, heterozygous; WT, wild type.

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Fig2. Detection of hANGPTL3 and mANGPTL3 expression in serum by ELISA. Abbr. HO, homozygous; WT, wild type.

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