hAPRIL

Background : C57BL/6Smoc

Catalog : NM-HU-220521

Strain Name : C57BL/6Smoc-Tnfsf13em(hTNFSF13)Smoc

Gene Summary

Gene Name

Model Description

The endogenous mouse Tnfsf13 gene was replaced by human TNFSF13 gene.

Validation Data

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Fig.1 Detection of TNFSF13 expression in lung by RT-PCR. 

Wild type: only one band at 180 bp with primers F1/R1 (mTnfsf13);

Homozygous: only one band at 217 bp with primers F2/R2 (hTNFSF13).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

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Fig.2 Detection of hTNFSF13 expression on CD11bcells in Peripheral blood and Bone marrow in hAPRIL mice.

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Fig.3 Detection of hTNFSF13 expression on CD11b+ cells in Peripheral blood and Bone marrow in hAPRIL mice.

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