hCCL4

Background : C57BL/6Smoc

Catalog : NM-HU-210013

Strain Name :

C57BL/6Smoc-Ccl4em1(hCCL4)/Smoc

Gene Summary

Gene Name
  • Synonyms :

    Mip, Scy, Act-, MIP-, Act-2, Mip1b, Scya4, AT744., MIP-1B, AT744.1

  • NCBI ID :

    20303

  • MGI ID :

    98261

  • Ensembl ID :

    ENSMUSG00000018930

  • Strain State :

    胚胎冻存

Model Description

The endogenous mice Ccl4 gene was replaced by human CCL4 gene

Validation Data

image.png

Fig1. Detection of CCL4 expression in small intestine, spleen and  thymus by RT-PCR. Wild type: only one band at 242 bp with primers F1/R1(mCcl4); Homozygous: only one band at 144 bp with primers F2/R2(hCCL4); Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig 2. Detection of hCCL4 expression in plasma by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type. Note. hCCL4 and C57BL/6 mice were i.p. injected with LPS(20mg/kg) for 6h.

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