Strain Model Specification

hCCL4

Strain Name C57BL/6Smoc-Ccl4tm1(hCCL4)/Smoc
Catalog Number NM-HU-210013
Genetic Background C57BL/6Smoc
Gene Symbol Ccl4
Synonyms Mip, Scy, Act-, MIP-, Act-2, Mip1b, Scya4, AT744., MIP-1B, AT744.1
NCBI ID 20303 ↗
MGI ID 98261 ↗
Ensembl ID ENSMUSG00000018930 ↗
Strain State Embryo cryopreservation
Research Application drug screening

Validation Data

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Fig1. Detection of CCL4 expression in small intestine, spleen and  thymus by RT-PCR. Wild type: only one band at 242 bp with primers F1/R1(mCcl4); Homozygous: only one band at 144 bp with primers F2/R2(hCCL4); Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig 2. Detection of hCCL4 expression in plasma by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type. Note. hCCL4 and C57BL/6 mice were i.p. injected with LPS(20mg/kg) for 6h.