Strain Model Specification

hCCR5

Strain Name C57BL/6Smoc-Ccr5tm1(hCCR5)Smoc
Catalog Number NM-HU-2000065
Genetic Background C57BL/6Smoc
Gene Symbol Ccr5
Synonyms AM4-7, CD195, Cmkbr5
NCBI ID 12774 ↗
MGI ID 107182 ↗
Ensembl ID ENSMUSG00000079227 ↗
Strain State Embryo cryopreservation
Research Application Immunotherapy,drug screening

Validation Data

NM-HU-2000065 hCCR5.png

Fig1. Analysis of CCR5 gene expression in the spleen by RT-PCR.

Mouse Ccr5 mRNA was detectable by P1/2(869bp), human CCR5 mRNA was detectable by P1/3(607bp), 

M:100bp Plus DNA ladder from Transgen (BM311). The heterozygous KI mouse expresses both human CCR5 and mouse Ccr5 in the spleen.