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hCD20(2)

Background : C57BL/6Smoc

Catalog : NM-HU-200114

Strain Name :

C57BL/6Smoc-Ms4a1^{tm2 (hCD20)Smoc}

Gene Summary

Gene Name

Synonyms :
cd20, Ly-44, Ms4a1, AA960661
NCBI ID :
12482
MGI ID :
88321
Ensembl ID :
ENSMUSG00000024673
Strain State :
Repository Live

Model Description

Extracellular and transmembrane region of the endogenous mouse Ms4a1 gene was replaced by corresponding region of human CD20 gene. While hCD20(Stock No.NM-HU-190068) mice function similarly to hCD20(2) mice,for more detailed information please contact our technical advisor.

Validation Data

Fig1. Detection of hCD20 expression on mCD19+ B cells in blood in hCD20 knockin mice.

Fig2. Rituximab can bind to lymphocytes of hCD20 knockin mice.

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