hCD28

Background : C57BL/6Smoc

Catalog : NM-HU-190011

Strain Name :

C57BL/6Smoc-Cd28em2(hCD28)Smoc

Gene Summary

Gene Name

Model Description

The endogenous mouse Cd28 gene was replaced by human CD28 gene.

Validation Data

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Fig1. Expression characterization of hCD28 on T cells in blood in heterozygous hCD28 KI mice.

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Fig2. Expression characterization of hCD28 on CD4+ and CD8+ T cells in blood in heterozygous hCD28 KI mice.

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Fig3. Expression characterization of hCD28 on CD4+ and CD8+ T cells in blood in homozygous hCD28 KI mice.

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Fig4. Cytokine release post stimulation with anti-CD28 antibodies in vitro.

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