hCD5(2)

Background : C57BL/6Smoc

Catalog : NM-HU-220579

Strain Name : C57BL/6Smoc-Cd5tm(hCD5)Smoc

Gene Summary

Gene Name

Model Description

The endogenous mouse Cd5 gene was replaced by human CD5 gene.

Validation Data

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Fig.1 Detection of CD5 expression in thymus by RT-PCR. 

Wild type: only one band at 138 bp with primers F1/R1 (mCd5);

Homozygous: only one band at 350 bp with primers F2/R2 (hCD5).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

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Fig.2 Detection of hCD5 expression in T cells and B cells in Blood in hCD5(2) KI mice.

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Fig.3 Detection of hCD5 expression in T cells and B cells in Spleen in hCD5(2) KI mice.

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Fig.4 Analysis of leukocytes cell subpopulation in Blood and spleen.

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