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Home / Humanized Models / Immune Checkpoints / hCTLA-4/4-1BB

hCTLA-4/4-1BB

Background : C57BL/6Smoc

Catalog : NM-HU-18020

Strain Name :

C57BL/6Smoc-Ctla4em1(hCTLA4) Tnfrsf9em1(hTNFRSF9) /Smoc

Gene Summary

Gene Name

Model Description

This CTLA4 and 4-1BB double knockin strain is established by crossing CTLA4-HU and 4-1BB-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

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