Strain Model Specification

hF11

Strain Name C57BL/6Smoc-F11em1(hF11)/Smoc
Catalog Number NM-HU-210015
Genetic Background C57BL/6Smoc
Gene Symbol F11
Synonyms FX, FXI, PTA, Cf11, AI503996, 1600027G01Rik
NCBI ID 109821 ↗
MGI ID 99481 ↗
Ensembl ID ENSMUSG00000031645 ↗
Strain State Repository Live

Validation Data

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Fig1. Detection of F11 expression in liver by RT-PCR. 

Wild type: only one band at 364 bp with primers F1/R1(mF11);Homozygous: only one band at 364 bp with primers F2/R2(hF11); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig 2. Detection of hF11 expression in plasma by ELISA (RayBiotech, ELH-CoagFXI-1). 

Abbr. HO, homozygous; WT, wild type.

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Fig3. Detection of hF11 expression in plasma by ELISA (Abcam, ab108834). 

Abbr. HO, homozygous; WT, wild type.

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Fig4. Prothrombinogen time (PT), activated partial thromboplastin time (APTT), fibrinogen (FIB) in hF11 mice. A. 8-10 weeks of age; B. 10-12 weeks of age.