hGIPR

Background : C57BL/6Smoc

Catalog : NM-HU-225064

Strain Name : C57BL/6Smoc-Giprtm1(hGIPR)Smoc

Gene Summary

Gene Name

Model Description

The endogenous mouse Gipr gene was replaced by human GIPR gene.

Validation Data

image.png

Fig.1 Detection of GIPR expression in brain by RT-PCR. 

Wild type: only one band at 177 bp with primers F1/R1 (mGipr);

Homozygous: only one band at 343 bp with primers F2/R2 (hGIPR).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig. 2 Detection of human GIPR expression in hGIPR mice by WB. 

Abbr. M,marker;HO, homozygous; WT, wild type; BAT, brown adipose tissue.

Note. The anti-human GIPR Antibody cross-reacted with mouse GIPR and humanized GIPR.

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