hHLA-A11

Background : C57BL/6Smoc

Catalog : NM-HU-204987

Strain Name :

C57BL/6Smoc-H2-K1tm1(hHLA-A11)Smoc

Gene Summary

Gene Name
  • Synonyms :

    K-f, H-2K, H2-K, H2-D1, H2-K_p, H-2K(d)

  • NCBI ID :

    14972

  • MGI ID :

    95904

  • Ensembl ID :

    ENSMUSG00000061232

  • Strain State :

    Repository Live

Model Description

The endogenous mice H2-K1 gene was replaced by human HLA-A11 gene.

Validation Data

image.png

Fig1. Detection of HLA-A11 expression in liver and spleen by RT-PCR.

Wild type: only one band at 369 bp with primers F1/R1(mH2-k1);

Heterozygous: one band at 369 bp with primers F1/R1(mH2-k1) and one band at 215 bp with primers F2/R2(hHLA-A11).

Abbr. M, DNA marker; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of HLA-A11 expression in blood in HLA-A11 KI mice.

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