Strain Model Specification

hICOS/hICOSL

Strain Name C57BL/6Smoc-Icosltm1(hICOSLG) Icostm1(hICOS)/Smoc
Catalog Number NM-HU-18018
Genetic Background C57BL/6Smoc
Synonyms AILIM, CCLP, CRP-1, H4, Ly115, B7h, GI50, GL50, B7-H2, LICOS, B7RP-1, GL50-B, ICOS-L, Icoslg, Ly115l, AU044799, BG071784, mKIAA0653
NCBI ID 54167, 50723 ↗
MGI ID 1858745, 1354701 ↗
Ensembl ID ENSMUSG00000026009, ENSMUSG00000000732 ↗
Strain State Embryo cryopreservation
Research Application Immunotherapy,cancer research,drug screening

Validation Data

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Fig1. Detection of hICOSL expression on activated APCs in hICOSL KI mice and hICOS/hICOSL dKI mice. 

Note. The splenocyte-derived activated APCs were stimulated by LPS in vitro.

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Fig2. Detection of hICOS expression on splenocyte-derived activated T cells in hICOS/hICOSL dKI mice.