Home / Humanized Models / Immune Checkpoints / hICOSL(2)

hICOSL(2)

Background : C57BL/6Smoc

Catalog : NM-HU-2000068

Strain Name : C57BL/6Smoc-Icosl^{tm3(hICOSLG)/Smoc}

Gene Summary

Gene Name

Synonyms :
B7h, GI50, GL50, B7-H2, LICOS, B7RP-1, GL50-B, ICOS-L, Icoslg, Ly115l, AU044799, BG071784, mKIAA0653
NCBI ID :
50723
MGI ID :
1354701
Ensembl ID :
ENSMUSG00000000732
Pubmed :
Array
Strain State :
胚胎冻存

Model Description

The endogenous mouse Icosl gene was replaced by human ICOSLG gene. While hICOSL(Stock No.NM-HU-00095) mice function similarly to hICOSL(2) mice,for more detailed information please contact our technical advisor.

Validation Data

NM-HU-2000068 hICOSLG.png

Fig1. Analysis of ICOSLG gene expression in the spleen by RT-PCR.

Mouse Icoslg mRNA was detectable by P1/2(276bp), human ICOSLG mRNA was detectable by P1/3(406bp),

M:100bp Plus DNA ladder from Transgen (BM311). The heterozygous KI mouse expresses both human ICOSLG and mouse Icoslg in the spleen.

Related Strains

Product

Product Catalog

Background

hIL3(NMG)

NM-NSG-007

NOD

Inquire

huHSC-(NMG)

NM-NSG-017

huHSC

Inquire

R26-CAG-LSL-hFCGR2A-IRES-EGFP

NM-KI-200229

C57BL/6Smoc

Inquire

R26-CAG-LSL-hFCGR3A-IRES-tdTomato

NM-KI-200255

C57BL/6Smoc

Inquire

R26-CAG-LSL-hSOS-F-tdTomato

NM-KI-200020

C57BL/6Smoc

Inquire

hTNFRSF10C

NM-HU-230344

C57BL/6Smoc

Inquire

R26-CAG-LSL-hMLL-AF9-IRES-Luc-2A-tdTomato

NM-KI-190114

C57BL/6Smoc

Inquire

hANGPTL3(3)

NM-HU-210037

C57BL/6Smoc

Inquire

hTIM4

NM-HU-225042

C57BL/6Smoc

Inquire

hFCGR1A

NM-HU-2000072

C57BL/6Smoc

Inquire

More..

Contact Back to top