hIL10

Background : C57BL/6Smoc

Catalog : NM-HU-2000063

Strain Name : C57BL/6Smoc-Il10tm4(hIL10)/Smoc

Gene Summary

Gene Name

Model Description

The endogenous mouse Il10 gene was replaced by human IL10 gene.

Validation Data

image.png

Fig1. Detection of IL10 expression in bladder by RT-PCR. 

Wild type: only one band at 362 bp with primers F1/R1(mIl10);

Homozygous: only one band at 196 bp with primers F2/R2(hIL10).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig2. Detection of human and mouse IL10 expression in serum by ELISA (n=2). 

Abbr. HO, homozygous; WT, wild type.

Note. hIL10 and C57BL/6 mice were i.p. injected with LPS for 2h.



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