Strain Model Specification

hIL17A

Strain Name C57BL/6Smoc-Il17atm1(hIL17A)Smoc
Catalog Number NM-HU-00042
Genetic Background C57BL/6Smoc
Gene Symbol Il17a
Synonyms Il17
NCBI ID 16171 ↗
MGI ID 107364 ↗
Ensembl ID ENSMUSG00000025929 ↗
Strain State Embryo cryopreservation
Research Application Immunotherapy,cancer research,drug screening

Validation Data

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Fig1. Detection of IL-17A expression in Large Intestine by RT-PCR. Wild type: only one band at 100 bp with primers F1/R1(mIl-17a);Homozygous: only one band at 121 bp with primers F2/R2(hIL-17A); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig2. Expression of human IL17A in cell supernatant derived from splenocytes  of IL17A-HU homozygous mice is detected by Elisa.