hIL18

Background : C57BL/6Smoc

Catalog : NM-HU-210038

Strain Name :

C57BL/6Smoc-Il18tm1(hIL18)Smoc

Gene Summary

Gene Name

Model Description

The endogenous mice Il18 gene was replaced by human IL18 gene.

Validation Data

image.png

Fig1. Detection of IL18 expression in intestine, colon and spleen by RT-PCR. 

Wild type: only one band at 305 bp with primers F1/R1 (mIl18); Homozygous: only one band at 265 bp with primers F2/R2 (hIL18). 

Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of hIL18 expression in serum by ELISA (n=3). 

Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig3. Detection of mIL18 expression in serum by ELISA (n=3). 

Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

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