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hIl5

Background : C57BL/6Smoc

Catalog : NM-HU-190001

Strain Name :

C57BL/6Smoc-Il5^{tm3(hIL5)Smoc}

Gene Summary

Gene Name

Synonyms :
Il-5
NCBI ID :
16191
MGI ID :
96557
Ensembl ID :
ENSMUSG00000036117
Strain State :
胚胎冻存

Model Description

This IL5 humanized mouse model was established by replacing the mouse Il5 gene coding exons and introns with the human TLR9 corresponding sequence by homologous recombination.

Validation Data

Fig1. Detection of IL-5 expression in thymus by RT-PCR. Wild type: only one band at 206 bp with primers F1/R1(mIl-5);Homozygous: only one band at 207 bp with primers F2/R2(hIL-5); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.