Home / Humanized Models / Immune Checkpoints / hPD-1/hICOS(2)

hPD-1/hICOS(2)

Background : C57BL/6Smoc

Catalog : NM-HU-2000100

Strain Name : C57BL/6Smoc-Pdcd1^em1(hPDCD1)Icos^{em1(hICOS)Smoc}

Gene Summary

Gene Name

Synonyms :
Ly101
NCBI ID :
18566 54167
MGI ID :
104879 1858745
Ensembl ID :
ENSMUSG00000026285 ENSMUSG00000026009
Strain State :
胚胎冻存

Model Description

hPD-1(NM-HU-00015) was crossed with hICOS(2)(NM-HU-190030) to generate hPD-1/hICOS(2).

Validation Data

Fig1. Detection of PD1 expression on activated T cells in splenocyte in hPD-1/hICOS(2) dKI mice.

Fig2. Detection of human ICOS expression on activated T cells in splenocyte in hPD-1/hICOS(2) dKI mice.

Fig3. Detection of mouse ICOS expression on activated T cells in splenocyte in hPD-1/hICOS(2) dKI mice.

Related Strains

Product

Product Catalog

Background

hIL3(NMG)

NM-NSG-007

NOD

Inquire

huHSC-(NMG)

NM-NSG-017

huHSC

Inquire

R26-CAG-LSL-hFCGR2A-IRES-EGFP

NM-KI-200229

C57BL/6Smoc

Inquire

R26-CAG-LSL-hFCGR3A-IRES-tdTomato

NM-KI-200255

C57BL/6Smoc

Inquire

R26-CAG-LSL-hSOS-F-tdTomato

NM-KI-200020

C57BL/6Smoc

Inquire

hTNFRSF10C

NM-HU-230344

C57BL/6Smoc

Inquire

R26-CAG-LSL-hMLL-AF9-IRES-Luc-2A-tdTomato

NM-KI-190114

C57BL/6Smoc

Inquire

hANGPTL3(3)

NM-HU-210037

C57BL/6Smoc

Inquire

hTIM4

NM-HU-225042

C57BL/6Smoc

Inquire

hFCGR1A

NM-HU-2000072

C57BL/6Smoc

Inquire

More..

Contact Back to top