hPSCA

Background : C57BL/6Smoc

Catalog : NM-HU-230059

Strain Name :

C57BL/6Smoc-Pscaem(hPSCA)Smoc

Gene Summary

Gene Name

Model Description

The endogenous mouse Psca gene was replaced by human PSCA gene.

Validation Data

image.png

Fig.1 Detection of PSCA expression in stomach by RT-PCR. 

Wild type: only one band at 140 bp with primers F1/R1(mPsca);

Homozygous: only one band at 154 bp with primers F2/R2(hPSCA).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human PSCA expression in hPSCA mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous.

Note. The anti-human PSCA antibody cross-reacted with mouse PSCA and humanized PSCA. Arrow indicates expected molecular weight and asterisk indicates a nonspecific band.

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