hPTGDR2

Background : C57BL/6Smoc

Catalog : NM-HU-225033

Strain Name : C57BL/6Smoc-Ptgdr2em1(hPTGDR2)Smoc

Gene Summary

Gene Name

Model Description

The endogenous mouse Ptgdr2 gene was replaced by human PTGDR2 gene.

Validation Data

image.png

Fig1. Detection of PTGDR2 expression in brain, stomach, colon and ovary by RT-PCR. 

Wild type: only one band at 227 bp with primers F1/R1(mPtgdr2);

Homozygous: only one band at 263 bp with primers F2/R2(hPTGDR2); 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig2. Detection of PTGDR2 expression on eosinophils in spleen in C57BL/6 and hPTGDR2 KI mice.

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