hPVRIG

Background : C57BL/6Smoc

Catalog : NM-HU-210008

Strain Name :

C57BL/6Smoc-Pvrigem1(hPVRIG)/Smoc

Gene Summary

Gene Name

Model Description

The endogenous mice Pvrig gene was replaced by human PVRIG gene While hPVRIG(2)(Stock No.NM-HU-215013) mice function similarly to hPVRIG mice, for more detailed information please contact our technical advisor.

Validation Data

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Fig1. Detection of PVRIG expression in spleen by RT-PCR. 

Wild type: only one band at 291 bp with primers F1/R1(mPvrig); Homozygous: only one band at 351 bp with primers F2/R2(hPVRIG); Abbr. M, DNA marker; HO, homozygous; WT, wild type.

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Fig2. Detection of hPVRIG expression in Daudi cells.

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Fig3. Detection of hPVRIG expression in Spleen in hPVRIG KI mice. 

Note. The anti-human CD112R (PVRIG) Antibody cross-reacted with mPVRIG and humanized PVRIG.

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Fig4. Detection of hPVRIG expression in Blood in hPVRIG KI mice. 

Note. The anti-human CD112R (PVRIG) Antibody cross-reacted with mPVRIG and humanized PVRIG.

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