hPVRL2

Background : C57BL/6Smoc

Catalog : NM-HU-2000084

Strain Name : C57BL/6Smoc-Nectin2tm1(hNECTIN2)/Smoc

Gene Summary

Gene Name
  • Synonyms :

    MPH, Pvr, Pvs, Cd112, Pvrl2, AI325026, AI987993, nectin-2

  • NCBI ID :

    19294

  • MGI ID :

    97822

  • Ensembl ID :

    ENSMUSG00000062300

  • Strain State :

    胚胎冻存

Model Description

The endogenous mouse Nectin2 gene was replaced by human PVRL2 gene.

Validation Data

image.png

Fig1. Detection of PVRL2 expression in duodenum and large Intestine by RT-PCR. 

Wild type: only one band at 342 bp with primers F1/R1 (mPvrl2);

Homozygous: only one band at 228 bp with primers F2/R2 (hPVRL2);

Abbr. M, DNA marker; HO, homozygous;  WT, wild type.

image.png

Fig2. Detection of human PVRL2 expression in duodenum and large Intestine in hPVRL2 KI mice. 

image.png

Fig3. Detection of hPVRL2 expression on marcophages and dendritic cells in hPVRL2 KI mice.

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