Cd33l3, EG620235, SIGLEC-I
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Fig1. In vivo validation of humanized SIGLEC15 mice. Humanized SIGLEC15 mice were inoculated with MC38 colon cancer cells, and were randomly assigned into different groups when the tumors grew to a volume of 100 mm3. Human-specifc, SIGLEC15 antibody ( 5G12-hIgG1 ) was given twice a week (BIW) for two weeks (In collaboration with Crownbio).
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