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hSIRPA(2)

Background : C57BL/6Smoc

Catalog : NM-HU-18015

Strain Name : C57BL/6Smoc-Sirpa^{tm2(hSIRPA)Smoc}

Gene Summary

Gene Name

Synonyms :
Bit, P84, SIRP, SHP-1, CD172a, Ptpns1, SHPS-1, AI835480
NCBI ID :
19261
MGI ID :
108563
Ensembl ID :
ENSMUSG00000037902
Pubmed :
Array
Strain State :
胚胎冻存

Model Description

The endogenous mouse Sirpa gene was replaced by human SIRPA gene . While hSIRPA (Stock No.NM-HU-00119) have been pulled from shelves for some reasons.

Validation Data

sirpa 流式.png

Figure 1. Detection of SIRPA expression in peripheral blood cells of humanized SIRPA mice.The FACS results of peripheral blood cells showed that the active expression of humanized SIRPA was detected in B cells and macrophage cells collected from heterozygous humanized SIRPA mice.(Completed in collaboration with CrownBio).

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More..

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