hTIGIT/hPVR

Background : C57BL/6Smoc

Catalog : NM-HU-2000091

Strain Name : C57BL/6Smoc-Tigitem1(hTIGIT)Pvrem1(hPVR)Smoc

Gene Summary

Gene Name

Model Description

These mice are obtained through breeding of two single gene humanized mice.

Validation Data

TIGIT.png

Fig.1 Splenocytes from homozygous TIGIT&PVR mice were analyzed by flow cytometry after activation. mTIGIT+ cells were detectable in wild type (WT) C57BL/6, while hTIGIT+ cells were detectable in the homozygous TIGIT&PVR mice. 

PVR.png

Fig.2 Splenocytes from homozygous TIGIT&PVR mice were analyzed by flow cytometry after activation. mPVR+ cells were detectable in wild type (WT) C57BL/6, while hPVR + cells were detectable in the homozygous TIGIT&PVR mice.

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