hTLR2

Background : C57BL/6Smoc

Catalog : NM-HU-190066

Strain Name : C57BL/6Smoc-Tlr2em2(hTLR2)Smoc

Gene Summary

Gene Name

Model Description

The endogenous mouse Tlr2 gene was replaced by human TLR2 gene.

Validation Data

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Fig1. Strain specific hTLR2 expression analysis in homozygous hTLR2 mice by flow cytometry. Macrophages of PBMC were collected from WT and homozygous hTLR2 mice, and analyzed by flow cytometry with species-specific anti-hTLR2 and anti-mTLR2 antibody.  hTLR2 was detectable in a subset of macrophages in homozygous hTLR2 mice, and the mTLR2 was not expressed.

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